Differential Ventures

Differential Ventures is an AI-native venture capital firm led by data scientists and entrepreneurs, focusing on data-centric B2B technology companies. They invest in early-stage startups, typically at the pre-seed and seed stages, with initial check sizes ranging from $250,000 to $3,000,000. Their primary investment themes include AI-Powered Business, Advancing the ML Technology Stack, The Future of Engineering and Infrastructure, and Responsible Data Management and Information Analysis.

The firm emphasizes providing hands-on support to portfolio companies, leveraging their team's extensive operational, technical, and investing experience to assist with challenges such as critical hires and complex technical hurdles.

Differential Ventures has made 44 investments, with their most recent investment on September 16, 2025, when PostSig raised an undisclosed amount. They have raised two funds, with the latest being Differential Venture Capital Fund II, LP, announced on June 30, 2021. The firm has made six diversity investments, with the most recent on June 1, 2023, when Shader raised an undisclosed amount.

Their portfolio includes companies such as Hatch.AI, FlowFi, Scope Zero, and Pienso. The firm's geographical focus includes the United States, Canada, and Israel, and they invest in sectors such as Artificial Intelligence, Machine Learning, Big Data & Analytics, Cybersecurity, FinTech, Internet of Things, SaaS, and Enterprise.

Differential Ventures is headquartered at 350 Park Avenue, FL 27, New York, NY 10022, United States. They can be contacted via email at info@differential.vc or by phone at (212) 300-2879. Their website is https://www.differential.vc.